Amyotrophic Lateral Sclerosis
Cognitive-Communication Treatment

External Scientific Evidence

Evidence-Based Practice Guidelines

American Academy of Neurology; American Academy of Neuromuscular and Electrodiagnostic Medicine    Practice Parameter Update: The Care of the Patient with Amyotrophic Lateral Sclerosis: Multidisciplinary Care, Symptom Management, and Cognitive/Behavioral Impairment (An Evidence-Based Review). Report of the Quality Standards Subcommittee of the American Academy of Neurology Miller, R. G., Jackson, C. E., et al. (2009). Neurology, 73(15), 1227-1233. Added: July 2011

 

Description

This guideline and corresponding systematic review is an update of a 1999 Practice Parameter on the care and management of individuals with amyotrophic lateral sclerosis (ALS). The primary audience intended for this guideline is neurologists. The recommendations are classified A, B, C or U, based on the strength and consistency of evidence. Level A recommendations are "established as effective, ineffective or harmful" and based on evidence from consistent high quality randomized controlled trials (RCTs). Level B recommendations are "probably effective, ineffective or harmful" and based on evidence from a high quality RCT or consistent evidence from two or more lower quality RCTs. Level C recommendations are "possibly effective, ineffective or harmful" and based on evidence from at least one low quality RCT or consistent evidence from two or more controlled trials. Level U recommendations indicate that the data is "inadequate or conflicting" and therefore the treatment is unproven. 

 

Recommendations

“There are insufficient data to support or refute the impact of cognitive and behavioral impairment on management in ALS” (Level U Recommendation) (p. 1231). 

 

» See full summary and quality ratings

 

  

 

 

Evidence-Based Systematic Reviews

No evidence-based systematic reviews were found.